Endocrine Abstracts

Objective: 8-Prenylnaringenin (8-PN) is a phytoestrogen discovered in hops. GH3 pituitary adenoma cells of the rat show a variety of responses to phytoestrogens in vitro. This in vitro study aims to analyze changes in hormone expression in GH3 cells treated with 8-PN.Methods: GH3 cells were incubated with 0.5–50 μM 8-PN for 4 h. Medium and ethanol served as controls. Changes in expression of growth hormone (GH) and prolactin (...